KM (Knowledge Management) systems have recently been adopted within the realm of enterprise management. On the other hand, data mining technology is widely acknowledged within Information systems' R&D Divisions. Specially, acquisition of meaningful information from Web usage data has become one of the most exciting eras. In this paper, we employ a Web based KM system and propose a framework for applying Web Usage Mining technology to KM data. As it turns out, task duration varies according to different user operations (...) such as referencing a table-of-contents page, down-loading a target file, and writing to a bulletin board. This in turn makes it possible to easily predict the purpose of the user's task. By taking these observations into account, we segmented access log data manually. These results were compared with results abstained by applying the constant interval method. Next, we obtained a segmentation rule of Web access logs by applying a machine-learning algorithm to manually segmented access logs as training data. Then, the newly obtained segmentation rule was compared with other known methods including the time interval method by evaluating their segmentation results in terms of recall and precision rates and it was shown that our rule attained the best results in both measures. Furthermore, the segmented data were fed to an association rule miner and the obtained association rules were utilized to modify the Web structure. (shrink)

The members of the Six gene family were identified as homologues of Drosophila sine oculis which is essential for compound-eye formation. The Six proteins are characterized by the Six domain and the Six-type homeodomain, both of which are essential for specific DNA binding and for cooperative interactions with Eya proteins. Mammals possess six Six genes which can be subdivided into three subclasses, and mutations of Six genes have been identified in human genetic disorders. Characterization of Six genes from various animal (...) phyla revealed the antiquity of this gene family and roles of its members in several different developmental contexts. Some members retain conserved roles as components of the Pax-Six-Eya-Dach regulatory network, which may have been established in the common ancestor of all bilaterians as a toolbox controlling cell proliferation and cell movement during embryogenesis. Gene duplications and cis-regulatory changes may have provided a basis for diverse functions of Six genes in different animal lineages. (shrink)

This article extends the concept of symmetry to ethics. Using the case of canola in Canada, the authors argue that grades and standards simultaneously subject humans and nonhumans to rites of passage that test their "goodness. " Then, they further develop a tentative typology of standards. The authors argue that these standards allow something resembling the neoclassical market to be established, create the conditions for economic analysis, and allocate power among human actors.

In June 2017, Japanese and Korean authors published the results of the CREATE‐X trial in the New England Journal of Medicine (NEJM). After we identified their inadequate disclosures of Financial Conflict of Interests (FCOIs), the authors made a post‐publication correction of their FCOIs. The purpose of this study is to evaluate the accuracy of the post‐publication corrections by the Japanese authors of the CREATE‐X trial. All the Japanese authors of the CREATE‐X trial were included in the study. We determined the (...) payments received by these authors in 2016 using publicly available data published by 78 pharmaceutical companies based on the stipulated Japanese transparency guidelines. We retrieved the original and revised versions of the FCOI disclosures as published on the NEJM website, and compared the payments reported by the pharmaceutical companies and the original and revised FCOI disclosures of the authors. Of the 12 authors, nine received payments made by the drug manufacturer involved in the CREATE‐X trial. Of these nine, only three (33.3%) originally disclosed their relationships, and another three (33.3%) later disclosed such relationships in the post‐publication corrections. Similarly, of the 11 receiving at least one payment from other manufacturers of breast cancer products, none correctly disclosed the payments in the original or the revised disclosure. In the CREATE‐X trial, FCOIs with pharmaceutical companies were not properly disclosed by 11 of the 12 Japanese authors, even after the post‐publication corrections, which highlights the need to pay more attention to the accuracy of FCOI disclosures in academic publications. (shrink)

The sophisticated function of the central nervous system (CNS) is largely supported by proper interactions between neural cells and blood vessels. Accumulating evidence has demonstrated that neurons and glial cells support the formation of blood vessels, which in turn, act as migratory scaffolds for these cell types. Neural progenitors are also involved in the regulation of blood vessel formation. This mutual interaction between neural cells and blood vessels is elegantly controlled by several chemokines, growth factors, extracellular matrix, and adhesion molecules (...) such as integrins. Recent research has revealed that newly migrating cell types along blood vessels repel other preexisting migrating cell types, causing them to detach from the blood vessels. In this review, we discuss vascular formation and cell migration, particularly during development. Moreover, we discuss how the crosstalk between blood vessels and neurons and glial cells could be related to neurodevelopmental disorders. (shrink)

In nature, cells face a variety of stresses that cause physical damage to the plasma membrane and cell wall. It is well established that evolutionarily conserved cell cycle checkpoints monitor various cellular perturbations, including DNA damage and spindle misalignment. However, the ability of these cell cycle checkpoints to sense a damaged plasma membrane/cell wall is poorly understood. To the best of our knowledge, our recent paper described the first example of such a checkpoint, using budding yeast as a model. In (...) this review, we will discuss this important question as well as provide hypothetical explanations to be tested in the future. (shrink)

In the long run, changes in society, both local and global, are inevitable. What, then, is and should be the relation between a general theory of law and social change? In the 1995 Kobe Lecture in Japan, Josef Raz said, “By and large, only bad theory can lead to change.” But a ‘good theory’, intended only to describe the normative world and not directly to change it or society, enlightens us in a way that changes our outlook in one way (...) or another. As our picture of the world changes, to that extent the change will be reflected in our practice. The change in practice in turn will affect society bringing about its change in the long run. That change can be either what was intended by the theory or an unintended consequence of it, sometimes favorable and sometimes disastrous. A theory may change the course of things as well by putting a halt to change. But if we can tell in advance that the theory will not lead to any social change whatsoever, it only means that the theory is trivial, or valueless even as a description. (shrink)

The form of higher plants is largely dependent upon cell division and expansion patterns. Taking a genetic approach, Takahashi et al.(1) have identified a regulatory molecule in Arabidopsis thaliana called DIMINUTO (DIM), which is involved in determining the degree and direction of plant cell expansion. Their extensive characterization of a dim mutant suggested a direct involvement of the DIM gene in regulating cell elongation, perhaps by modulating the expression of structural genes which determine the orientation and elasticity of the cell (...) wall. (shrink)

What Does Only Assert and Entail? This paper investigates the semantics of English only and two equivalent expressions in Japanese -dake and -shika, giving attention to two aspects: the debate over the status of two propositions that are involved in the use of ONLY expressions and the semantic and pragmatic differences among ONLY items, if any. We claim that a sentence with ONLY expressions entails both the affirmative and negative propositions. This view raises issues with Horn's original claim as well (...) as van Rooij and Schulz's while supporting Atlas and Horn. We claim then that the difference in strength between the affirmative and negative propositions emerges from what is asserted by that sentence. One of the bases for our claim is that there is a significant difference in behavior between entailment and assertion of a given sentence, following Horn. This difference explains the difference between -dake on the one hand and -shika and -only on the other: -dake differs from only and -shika in that it asserts the affirmative proposition while -shika and only asserts the negative proposition. (shrink)

Translated text is chapt. 7, pt. 2 of Kirisutokyō no benshō.

We proposed the Standards of Conducts to provide a general framework that will serve as the basis for guiding each biostatistician and stem cell researcher to formulate their personal standards, rather than as rules with which they are required to comply. Given the responsibility and characteristics of their work, they are expected to maintain independence and work autonomously as professionals. Each of the Standards of Conducts comprises a preamble, mission and values to uphold, Standards of Conducts, and background. When one (...) internalizes “self-formulated” standards, to make excuses for oneself would be akin to a self-betrayal; responsible actions can be anticipated. If one begins and continues to consider “who I am and what do I work for,” this will become their inner energy, and a source of motivation and pride to inspire oneself. In addition, this aspirational style might help citizens to recognize the autonomous stance of the professional body and that they share the same values. (shrink)

The numbers of unfortunate deaths in the twentieth century were the highest compared with any previous century. Such an increase obviates any excuses The idea of technological possibility itself is one of the most basic causes of the destruction of nature in our new human milieu today, the technological conjuncture. But we human beings are also a part of nature. Therefore, without a new ethics understood as eco-ethica nature itself cannot fulfill the necessary conditions for the survival of human beings. (...) For the first time owing to the technological conjuncture human beings bear full responsibility for all human beings tomorrow, for the future of humanity. Nature is no longer just a means to be exploited for the development of human civilization but also a model for how human civilization is to survive. The two great humanistic traditions, Western and Eastern, have developed the same content at the same level. People in the two worlds are really preparing a new cosmopolitanism. (shrink)

For a prime k, the embeddability of finite lattices are discussed for various kind of the MODkP degrees of recursive sets. In particular, all finite lattices are embeddable into the MODkP Turing degrees, whereas the non distributive lattice M3 is embeddable into the MOD2P many-one degrees but N5 is not.

法・正義・自由をめぐる根源的思考。法概念についての抽象的な議論から裁判員制度等の実践的な問題まで、法哲学が提起する思考のスタイル。.

In this paper, we conceptually explore the role of empathy as a connectedness organising mechanism. We expand ideas underlying positive organisational scholarship and examine leading-edge studies from neuroscience and quantum physics that give support to our claims. The perspective we propose has profound implications regarding how we organise and how we manage. First, we argue that empathy enhances connectedness through the unconscious sharing of neuro-pathways that dissolves the barriers between self and other. This sharing encourages the integration of affective and (...) cognitive consciousness which facilitates the ability to find common ground for solution building. Second, empathy enhances connectedness through altruistic action. In giving to others, feelings of joy and harmony are activated. This in turn allows personal freedom to be enriched and transcendence from the rational ego-self is reduced to develop a more expansive, integrated and enlightened state underlying connectedness. Finally, empathy enhances connectedness which results in sharing the quantum field of coherence where there is little separation between self and other. This means living beyond self-interest in a coherent world based upon interdependent wholeness rather than atomization and separation. Empathy allows us to find that state of coherent connectedness. (shrink)

Social dilemmas, in which individually selfish behavior leads to collectively deficient outcomes, continue to be an important topic of research because of their ubiquity. The present research with Japanese participants replicates, with slight modifications, public goods games previously run in the United States. In contrast to recent work showing profound cross-cultural differences, the results of two studies reported here show remarkable cross-cultural similarities. Specifically, results suggest that (1) as in the U.S., allowing incremental commitment to a public good is effective (...) at eliciting contributions, (2) individual differences in trust affect contributions, (3) the distribution of player types in the U.S. and Japan are very similar, and (4) the dynamics of play in the public goods games used here are strikingly parallel. These results are discussed in the context of the relationship between cross-cultural differences and economic institutional environments. (shrink)

The planet is experiencing a deep metamorphosis. The pressure that is being generated nowadays on the living can be felt in a human lifetime. The extreme speed of climate change and its impact on our ecosystem can no longer be ignored. When looking at the phenomenon of ecological resilience, we notice that after a disturbance, a shock on an ecosystem, like the burning of a forest, the resilient system rebuilds itself but not exactly as it was before, surprisingly new species (...) grow. In social systems, humans have the capacity to anticipate, adapt and invent new patterns of behaviours. In a world where everything is uncertain, moving, shifting, we are making an artistic proposal as an open dynamic system. We are developing two versions of the same HALO project to be presented on the sea and in public places. (shrink)

One’s generosity to others declines as a function of social distance, which is known as social discounting. We examined cultural similarities and differences in social discounting and the mediating roles of the two aspects of interdependence (self-expression and distinctiveness of the self) as well as the two aspects of independence (harmony-seeking and rejection avoidance). Using the same procedure that previous researchers used to test North Americans, Study 1 showed that compared to North Americans, Japanese discount more steeply a partner’s outcomes (...) compared to their own future outcomes, whereas the decrease in the subjective value of the partner’s outcomes accelerates less as a function of social distance. To examine the cultural similarities and differences in social discounting in more detail, Study 2 tested Japanese and Germans and found that the hyperbolic with exponent model fitted the participants’ discounting behaviors better than the other models, except for the loss condition in Germans where the utility of the q-exponential model was indicated. Moreover, although the social discounting rate was higher in Japanese than in Germans, the cultural difference was limited to the gain frame. However, the decline in a person’s generosity accelerated less as a function of social distance in Japanese than in Germans. Furthermore, the cultural difference in the social discounting in gains was mediated by the level of harmony-seeking, which was higher in Germans than in Japanese. Implications for individuals’ generosity against the backdrop of cultural characteristics are discussed. (shrink)

There is an increasing emphasis on clear disclosure of conflict of interest in medical communities, following repeated scientific frauds in clinical trials. However, incomplete COI statements continue to be prevalent in the medical community, as appears to have occurred in the Capecitabine for Residual Cancer as Adjuvant Therapy trial, which was recently published in the New England Journal of Medicine. The authors of the article did not clearly report the roles of the Japan Breast Cancer Research Group, a sponsor and (...) funder of the study, although a majority of the Japanese authors served in important positions in the organization. Furthermore, the conflict of interest related to Chugai Pharmaceutical Company, a Japanese distributor of capecitabine, was not correctly disclosed. More transparent statements of conflict of interest and clarification of sponsors and funders’ roles, as well as rigorous review by academic journals are required to fairly interpret the findings of clinical trials, including and beyond the single case of the CREATE-X trial. (shrink)

As Hegel suggests, there is no philosophy apart from the history of philosophy. Each philosophy represents the spirit peculiar to its own period. Heidegger, too, holds that every philosophy is the sound of Being, and the history of philosophy is the history of Being. This is true for the Kyoto School philosophy of modern Japan represented by Kitaro Nishida, Hajime Tanabe, and Tetsuro Watsuji, who made to endeavor to construct a new synthesis of Western and Eastern philosophy in the critical, (...) confrontational, and creative ways in the given historical contexts. In particular, Tanabe attempts at the dialectical unification of Christianity and Buddhism in the last resort from the standpoint of Absolute Nothingness. As, in Whitehead’s conception of process, actuality is composed of the past objective being as the given data and the present subjective act of becoming, so it might be highly significant to analyze the constitutive elements of Tanabe’s system of thought from the historical and comparative contexts. (shrink)

In this article I examine Lavoisier's collaboration with his wife in the translation of Kirwan's An essay on phlogiston into French (Essai sur le phlogistique, 1788). This translation is a kind of counter attack by the school of French scholars around Lavoisier. Mrs Lavoisier is generally considered only to have translated Kirwan's book, not to have refuted it. Through a detailed analysis of the translation, of her manuscripts, and of other documents of the period, I conclude that Mrs Lavoisier not (...) only actively attacked the doctrine of phlogiston in her translation, but in the notes and preface to it as well. In addition to her high-level knowledge of chemistry, her close scientific relationship with her husband should be noted. In the first three parts of the translation, the two shared the work between them, in order to convine the readers. A show that Mrs Lavoisier advocated the study of gases from the point of view of their motions, and that she always believed that her husband's theory would prevail. Moreover, Lavoisier assessed his wife's talent at its true value. (shrink)

While much has been written about the uniquely Hawaiian take on the category “local” – usually in terms of resistance to colonization, the alternative or counterhegemonic – little has been written about “haole”, the trope that served to silhouette the “local” and has evolved in dialectical opposition to it. A term that emerged during the plantation era to represent working-class immigrant workers mostly from Asia, “local” is constructed by exclusion. It has evolved to represent solidarity against all “external forces” controlling (...) Hawai'i from without, such as land development, tourism and the military – all readily equated with haole, the visible sign of whiteness. The prevalence of the prescription “local vs. haole” in contemporary Hawai'i begs an inquiry into other interpretations that are being suppressed. This paper explores some suppressed histories, imaginings and subconscious aspects of identity in Hawai'i through the figure of the white person whose parents – and possibly great-great-great-grandparents – were born and raised in Hawai'i. (shrink)

Recent climate change statistics attribute over a quarter of carbon emissions to residential energy use in the United Kingdom. To address this, a building standard was introduced to aim to reduce the levels of carbon dioxide emissions and energy consumption. This paper analyzes how such an environmental standard reconfigures the sociotechnological relations and practices of housing professionals that design, construct, and manage social housing. We focus on how actors engage with the standard’s recommendation for incorporating low and zero carbon technologies (...) into new buildings. We identify diverse practices that emerge from these engagements, which, we contend, have significant consequences for the working relationships of professional actors and for renewable energy provision. By being entwined in, and generative of actors’ practices, we argue that the Code becomes part of the sociotechnological relationships and infrastructures that shape energy provision. (shrink)

In this collection on the Kyoto School of Philosophy, the author offers the reader Tanabe's religious philosophy, but also, and for the first time, his ...

Hajime Tanabe (1885-1962), the Kyoto- School philosopher of modern Japan, attempts to interpret Aristotle's ontology as being involved in the logic of self-identical being without self-negative conversion in action from his own dialectical perspective. For Tanabe, the eternal essence or Form is to be mediated by the dynamic character of matter, i.e., the temporality pertinent to the changing movement. For Aristotle, however, the essence or pure activity as the principle of being is devoid of such a dynamic mediation, but is (...) rather regarded as the past being, i.e., what it should be originally and eternally. In other words, for Aristotle, evil and matter are the lacks of goodness and the eternal Form that are identical with the essence of the individual substance. Evil is to be self-negatively mediated to goodness in free action through conversion in Tanabe's perspective. Movement pertaining to matter is not simply an incompletion of pure activity, but is rather self-negatively converted into the activity as the transcendent principle of the dialectical unification of time and eternity, matter and Form, evil and Goodness. The individual existence has freedom to unify the self-contradistinctive opposed moments, i.e., subjective action and objective being in a way of mutually negating conversion. The difference between Tanabe and Aristotle lies in that for Tanabe practice is relevant to the future, whereas for Aristotle contemplation is concerned with eternity as invariable and imperishable being since the past. While Aristotle's logic is confined to the self-identity of being in contemplation, Tanabe's logic is structured by the triadic elements of individuality, species as the relative universal, and genus as the absolute universal in terms of the negative conversion in action. (shrink)

Hajime Tanabe (1885-1962), the Kyoto- School philosopher of modern Japan, attempts to interpret Aristotle's ontology as being involved in the logic of self-identical being without self-negative conversion in action from his own dialectical perspective. For Tanabe, the eternal essence or Form is to be mediated by the dynamic character of matter, i.e., the temporality pertinent to the changing movement. For Aristotle, however, the essence or pure activity as the principle of being is devoid of such a dynamic mediation, but is (...) rather regarded as the past being, i.e., what it should be originally and eternally. In other words, for Aristotle, evil and matter are the lacks of goodness and the eternal Form that are identical with the essence of the individual substance. Evil is to be self-negatively mediated to goodness in free action through conversion in Tanabe's perspective. Movement pertaining to matter is not simply an incompletion of pure activity, but is rather self-negatively converted into the activity as the transcendent principle of the dialectical unification of time and eternity, matter and Form, evil and Goodness. The individual existence has freedom to unify the self-contradistinctive opposed moments, i.e., subjective action and objective being in a way of mutually negating conversion. The difference between Tanabe and Aristotle lies in that for Tanabe practice is relevant to the future, whereas for Aristotle contemplation is concerned with eternity as invariable and imperishable being since the past. While Aristotle's logic is confined to the self-identity of being in contemplation, Tanabe's logic is structured by the triadic elements of individuality, species as the relative universal, and genus as the absolute universal in terms of the negative conversion in action. (shrink)

Tanabe Hajime, another pole of the so-called Kyoto-School of Philosophy of modern Japan, attempts to construct a dialectical, triadic logic of genus, species and individual as a creative synthesis between Eastern and Western philosophy. Although the formal pattern of his method is influenced by the Hegelian dialectic, the way of his thinking is rather prevailed by Kantian dualism. This makes a sharp contrast to his mentor Nishida Kitaro, whose logic of Topos or Place qua Absolute Nothingness is criticized as all-embracing (...) and static in character by him. The difference between them might be parallel to that of Greek and Latin theology concerning the Trinity. Tanabe never presupposes any preexistent entity as the primordial One in the eternal dimension, but rather maintains the individuality as the free subjective agent in the field of history. The dichotomy between the universal and the individual is overcome in and through the mediation of the third term— the species — as the negatively self-realized, specific form of the genus. The species, however, turns out to be the self-estrangement, when it loses the perpetually negative mediation of the free subjective activity of the individual. (shrink)

Tanabe Hajime, the Kyoto School philosopher of modern Japan, proposes a new idea of the relationship between religion and politics in terms of the triadic logic of species that is motivated by the religious moment of repentance. Even the state existence has the inherently radical evil as in the case of the individual person, due to its duality of the species level of being. This means that the state existence is on the way of actualization of the genus like universality, (...) while always involving in the regression into the past substrative being which prevents it from realizing its own universality. In other words, the state existence is not absolute as such but rather a balanced being between ideality and reality, absolute and relative. This entails that politics is in need of perpetual reformation in connection with the religious act of repentance for sin and evil deeply lurked in human beings from time immemorial. Tanabe’s Logic of Species as the dialectic elucidates the negative mediation of politics and religion from the metanoetic perspective and sheds a new light on the relation of world religion and politics today. (shrink)

The historical origins of the Kyoto School of Philosophy of modern Japan, represented by Kitaro Nishida and Hajime Tanabe, may be derived from both the ancient Chinese idea of Change and the ancient Indian Upanishadic idea of the mutual identity of Brahman and Atman. The ancient Chinese idea of Change signifies change as well as non-change, and even their dialectical unification. Both origins are structured by the self-identity of the opposed in logic, and these historical prototypes have been developed into (...) the various forms of Confucian, Taoist, and Buddhist philosophy. The notion of Nothingness or Emptiness rather than Being has been set up as the fundamental principle. The principle of Nothingness as ultimate reality has been connected with the logic of self-identity of theopposed, and this is evident in Nishida’s concept of the self-identity in absolute contradistinction that is equivalent to the Place of Absolute Nothingness. Even though Nishida’s idea of Place is directly and explicitly influenced by the ancient Greek idea of Topos, it has indirectly and implicitly been affected by the traditional agricultural society as well, in which the land is regarded as the self-identical substratum despite the cyclic time of the four-seasons change. The ancient Chinese idea of Change also reflects the agricultural society in which the cyclic time plays an important role on the basis of the unchanging self-identical land as the underlying substratum. Nishida succeeds in establishing the new logical expression of Eastern traditional thought, deeply hidden in consciousness, in relation toWestern philosophy. The uniqueness of Nishida’s idea of Place may have its main source in the traditional agricultural background, and in this sense his way of thinking may be rural in character. On the other hand, Tanabe, though following Nishida at first, turns to making criticism of the mentor with the establishment of the triadic logic of species as the dialectic, which is characterized by the perpetual self-negating conversion in action. In contrast to Nishida, Tanabe represents the urban type of thinking, which is in pursuit of transforming in life. While Nishida’s idea of Absolute Nothingness has an affinity with the ancient Chinese philosopher Laotzu’s idea of Nothingness from and into which every entity comes and goes, Tanabe’s concept of Absolute Nothingness as the principle ofconversion is more closed to the Buddhist idea of sunyata, i.e., Emptiness, which is devoid of any substance in itself. As regards evil, the difference between them is obvious in that for Nishida evil and time or history disappear into the ultimate horizon or place of Nothingness with the tendency toward a kind of monism of goodness, whereas for Tanabe evil copes with goodness and retains its own status throughout, never being reduced to the opposed. Even if so, both of them, however, fail to construct a philosophy of history from the epochal or durational viewpoint, compared to Heidegger and Jaspers. (shrink)